Respiratory Rally

By *itsme* on Dec 23, 2009 | Reply

Severe acute respiratory syndrome (SARS) is a viral respiratory illness that first emerged in China in November 2002, and later spread through international travel to 29 countries worldwide.

What causes SARS?
SARS is caused by a virus called the SARS-associated coronavirus (SARS-CoV). It was first identified in April 2003 and is a member of the Coronaviridae family, which also includes many of the viruses that cause the common cold. Coronaviruses have been found in many different animal species including birds and mammals. SARS-CoV is thought to have passed from animals to humans through close contact, butchering or eating undercooked meat in parts of Southern China.
How does SARS spread?

* SARS is spread primarily by close person-to-person contact. In the context of SARS, close contact means having cared for or lived with someone with SARS or having direct contact with respiratory secretions or body fluids of a patient with SARS. (Examples of close contact include kissing or hugging, sharing eating or drinking utensils, talking to someone within 3 feet, and touching someone directly. Close contact does not include activities like walking by a person or sitting across a waiting room or office for a brief time.)
* The virus that causes SARS is transmitted by the spread of respiratory droplets produced when an infected person coughs or sneezes. When a person coughs or sneezes, small amounts of fluid are propelled for about 3 feet through the air and land on the mouth, nose or eyes of persons who are near by.
* The virus also can spread when a person touches a surface or object contaminated with these infectious droplets and then touches his or her mouth, nose, or eyes.
* It is possible that the SARS virus might spread more broadly through the air (airborne spread) or by other ways that are not now known.

Symptoms of SARS

For a severe respiratory illness to be SARS, there has to be a history of travel to a SARS affected area or close personal contact with a person with SARS, within ten days before symptoms start, this is called the epidemiological link. In general, SARS beginswith a high fever (temperature greater than 100.4°F [>38.0°C]). Other symptoms may include headache, an overall feeling of discomfort, and body aches. Some people also have mild respiratory symptoms at the outset. About 10% to 20% of patients have diarrhea. After 2 to 7 days, patients develop a dry cough, shortness of breath, and pneumonia.
How is SARS diagnosed?

Doctors suspect SARS if a patient has a fever of 38.0C or 100.4F, respiratory symptoms and history of travel to a SARS affected area or close contact with a known SARS patient within 10 days before the fever or respiratory symptoms started. Since the initial symptoms of SARS are similar to influenza or other respiratory illnesses, a high level of suspicion and an accurate history is needed to differentiate SARS from other illnesses. There are several laboratory tests used to detect SARS-CoV and other causes of respiratory illness. In some persons it may take as long as 28 days after the start of symptoms to have a definite laboratory diagnosis.
How do we protect ourselves from SARS?

If there are no known SARS cases in the world, we protect ourselves and others by following the usual infection control precautions. If you have a respiratory illness, with fever and cough, consider staying home, away from school or work to prevent giving it to others. If you are out in public, cover your mouth and nose with tissues when coughing or sneezing. Frequently wash your hands with soap or use alcohol hand sanitizers. If you are at a clinic or hospital inform the receptionist that you have a respiratory illness. Clinics may have a designated area for respiratory illness and may ask you to wear a mask to protect other patients and clinic staff. Talk to your doctor about a Flu shot which can protect you against influenza, another respiratory illness. If there is community transmission of SARS in any city in the world, the MDH will issue recommendations regarding precautions in Minnesota. We have learned that transmission of SARS was mainly among close personal contacts of ill persons and health care workers caring for them. It is unlikely that SARS can be acquired by walking or sitting across from a person with SARS. However, persons with SARS are advised to isolate themselves at home for 10 days after the resolution of fever, provided that their respiratory symptoms are improving.

In caring for a SARS patient at home strict infection control precautions should be followed.

* All persons in the household should carefully wash their hands frequently with soap or alcohol hand sanitizers, this should always be done after touching body fluids.
* Gloves can be used for direct contact with the patient or body fluids but should not replace hand washing.
* SARS patients should cover their mouth and nose when coughing or sneezing or if possibl
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By Keene on Dec 23, 2009 | Reply

Hi..

Here is an introductionary few lines about SARS but it sounds to me like you need More details so please read from the attached links below.

Severe acute respiratory syndrome (SARS) is a serious, potentially life-threatening viral infection caused by a previously unrecognized virus from the Coronaviridae family. This virus has been named the SARS-associated coronavirus (SARS-CoV).
The Coronaviruses cause diseases in pigs, birds, and other animals. Preliminary research indicates that SARS-CoV may have originated in livestock (eg, chickens, ducks) or small mammals. Chinese horseshoe bats, which carry SARS-like viruses with genetic homology to SARS-CoV, may have also had a role. From its reservoir, the virus may have mutated, allowing transmission to and infection of humans, perhaps facilitated by the proximity in which humans and livestock live in rural southern China.

existing coronaviruses include mammalian and avian viruses, contribute to numerous veterinary diseases (eg, feline infectious peritonitis, avian infectious bronchitis). The coronaviruses can also cause both upper and, more commonly, lower respiratory tract illness in humans (group 1 [human coronavirus 229E] and group 2 [human coronavirus OC43]).

The WHO reported that leaky, backed-up sewage pipes, fans, and a faulty ventilation system were likely responsible for a severe outbreak of SARS in the Amoy Gardens residential complex in Hong Kong. However, an analysis by the WHO, entitled " Status of the outbreak and lessons for the immediate future," on the distribution of cases at this development has suggested that transmission may have occurred within the complex via airborne, virus-laden aerosols.

Good luck

http://cmbi.bjmu.edu.cn/news/report/2007/95/14.pdf

http://www.microbiologybytes.com/virology/Coronaviruses.html

***********Specific Answer to your last Question***********

SARS initially manifests as a flulike syndrome that may progress to pneumonia, *****respiratory failure(please read about respiratory failure pathophysiology)******, and, in some cases, death. The mortality rate associated with SARS is significantly higher than that of influenza or other common respiratory tract infections.

SARS can result in significant illness and medical complications that require hospitalization, intensive care treatment, and mechanical ventilation.

* The mortality rate of SARS is higher than that of non-H5N1 influenza strains or other common respiratory tract infections.
* The overall mortality rate of SARS has been approximately 10%. According to the CDC and the WHO, the death rate among individuals older than 65 years exceeds 50%.
* The WHO has set the SARS containment period at 20 days. If no new cases of SARS are reported in a given area over a 20-day period, given the relatively short incubation period of the disease, the WHO considers SARS infections in that area to be contained.
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