why there is obstruction of bronchioles during expiration phase only in COPD?
November 6th, 2009 | by admin |COPD= chronic obstuctive pulmonary disease
will be thankful for the answers
Normally during inspiration … dilation of the airways occur … on expiration the lumen diameter decreases … in disease … dynamic airway closure occurs due to either inflammation and smooth muscle contraction …. or in the case of emphysema … destruction of the normal supporting structure of the alveoli and subsequent loss of recoil of the lung .. the alveolar walls are destroyed and as a result the bronchioles lose their structural support …. Thus, the bronchioles collapse when the air is exhaled.
One Response to “why there is obstruction of bronchioles during expiration phase only in COPD?”
By cryptoxmit on Nov 6, 2009 | Reply
Normally during inspiration … dilation of the airways occur … on expiration the lumen diameter decreases … in disease … dynamic airway closure occurs due to either inflammation and smooth muscle contraction …. or in the case of emphysema … destruction of the normal supporting structure of the alveoli and subsequent loss of recoil of the lung .. the alveolar walls are destroyed and as a result the bronchioles lose their structural support …. Thus, the bronchioles collapse when the air is exhaled.
References :
RRT-NPS, RPFT